To this day I consider [DDS] unreliable. I still have to use it now and then, on those aforementioned IBM computers.
Up until very recently, most of my clients were using DDS for system backup purposes, with almost no reported problems, even after years of usage. I have switched most of them to LTO due to increased capacity needs. The smallest LTO cartridge (LTO-1, which is now considered obsolete) has more capacity than DDS-160. Almost all of my clients on LTO are using LTO-3, which has a raw capacity of 400GB and a theoretical capacity with hardware compression of 800GB. Transfer rate on a system with SCSI U320 hardware, such as one of my Linux servers, is upwards of 27MB per second streaming to the tape, which is slightly better than the performance of a typical SATA hard disk in a PC.
Of those clients who are not on LTO, two are on DDS-160, one is still on DDS-4 (an old Windows box acting like a lame file server) and one client is using
RDX as the backup device. The smallest capacity RDX cartridge currently in distribution holds 500GB, with sizes going up to 3TB.
DDS cartridges have a reliable life expectancy of around 100 full passes, and the drives need to be cleaned regularly. It is the overuse of cartridges and failure to clean the drive when needed that contribute to the majority of DDS read/write errors. The brand of cartridge being used and the way in which cartridges are handled and stored can contribute to failures. There are only a few brands that I trust: Imation, H-P and Tandberg, in that order.
That said, I have no reservations about implementing DDS in situations where the limited capacity (by today's standards) is adequate.