The data sheet BDD posted shows the output on page 33. The Sep 13, 2010 WDC 65c22 data sheet has more diagrams & info on page 32, 33, 34, and 35, comparing their (always) totem-pole CMOS output on the W65C22
S and their inputs, to GTE's and Rockwell's which often have resistors in the pull-up circuit.
One application where I remember having problems was a fixture I made to test a 65c02 for information that was not in the data sheet, by using the workbench computer to control what instructions to give it and what cycle in each instruction to generate an NMI. All 16 bus bits of the processor under test, as well as its phase 0, R/W, Sync, RDY, NMI, IRQ, and RST went to I/O pins of VIAs on the workbench computer. (I had to use two VIAs, as one is not enough for so many lines.) My program printed the state of both buses and all these other pins at every cycle, one printed line per cycle. (It turns out that it would respond to NMI and start the interrupt sequence immediately when the instruction was done, without starting another instruction first, even if the interrupt hit during the last cycle, and even if an interrupt applied in an earlier cycle were removed before the instruction was finished.) Just to be safe, I connected the data lines to VIA pins through 3.3K resistors to avoid contention, in case I goofed in my program and made both to be outputs at the same time. Maximum current then would be only 1.5mA per pin. With the Rockwell VIA, it wouldn't work that way. The VIA inputs appeared to be high whether the processor data lines were trying to pull them down or not. I had to take out the resistors.
There have been other times too, where I wanted to drive them with something other than logic ICs, like having a passive pull-down so they would appear low unless something pulled them up. With a 150-ohm resistor there, the devices pulling them up would have to be too strong. To get even 2.4V on 150 ohms, you need 16mA per pin! Sure, you could add another IC for a driver, but why add more parts (possibly requiring an additional board) when you could just use the W65C22S with CMOS inputs. Coincidentally, Justin just posted an hour ago at
viewtopic.php?f=4&t=2735&p=29889#p29889 that he found a problem keeping his circuit from working was the NMOS 6522 not being able to pull up hard enough. A CMOS one would have had plenty of headroom to spare, being able to pull up much harder than needed.