actually this reminds me, i once planned to make a 65C02 or 65816 SBC in an arduino form factor so i could use it with one of those TFT Display + SD Shields.
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with the idea being that the entire thing could be self contained using the touchscreen as user input, the display as output, and the SD card to hold programs and such.
and if you were to slap a Li-Po battery + protection/charging circuitry on the back, you'd have a functional SBC without needing external wires... like a smartphone but worse in almost every way!
i made a rough layout for it to see if it were even possible to fit everything between the 2 connectors of the shield:
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and it seems like you can, and also stay below 100x100mm PCB size!
this board has a 65C02, 65C22, an SST39SF Flash (maybe like 8kB?), 128kB of RAM (maybe banked?), an ATF1504, and an FT240X for Serial.
this would already be quite the feature rich SBC, but keep in mind that i just placed stuff wherever it fit. so i didn't put any thought into routing all of this, so a 4 layer PCB might be required... which gets pretty pricey.
using the *FQP version of the 65C02 and 65C22 would free up quite a lot of space that would allow things to be placed a bit further apart from eachother, which would make routing easier.
and it might also be possible to use a 65816 instead of a 65C02, because there is only 128kB of RAM you would only need to capture 1 bit from the multiplexed Data/Address bus, which the ATF1504 should be able to handle.
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anyways i'm sorry if this doesn't really fit the topic, as it's more of a standalone SBC that is compatible with an Arduino shield, instead of being an SBC that aims to be as porgammable as an actual Arduino...